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Long-term maintenance therapy for patients with discrete aldosterone-producing adrenal adenomas who are judged to be poor operative risks or who decline surgery. ALDACTONE should be used only in those conditions described under Indications and Usage.

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Spironolactone,a competitive antagonist of aldosterone, is widely used as a diuretic and anthypertensive agent. Controlled studies in pregnant women show no evidence of fetal risk. The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net. It is also very important to stay upright until after you have eaten your first food of the day. Although adenosine, given during pharmacologic stress testing, is known to interact with various medications, the potential for this interaction may be overlooked if the culprit is present in a combination drug.